Alejandro Jodorowsky's Dune would have tripped you out

Apparently, eccentric genius filmmaker Alejandro Jodorowsky at one point set out to make a version of Dune for the screen that would simulate the effects of LSD, as he notes in the promo for an upcoming documentary about the failed project:

"I wanted to do a movie that would give the people who took LSD at that time the hallucinations that you get with that drug, but without hallucinating. I did not want LSD to be taken - I wanted to fabricate the drug's effects."

A true missed opportunity. As Slashfilm notes, "So he wanted to make a movie that replicated the effect of drug use? A lot of people have said and/or tried that, but Jodorowsky is one of the very few who seems likely to make it work."