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A really good reason not to take MDMA

Interdiction efforts even the Psychotrophe supports:

In a month-long investigation a team from Fauna and Flora International (FFI) uncovered the illegal distilleries deep in the forest of the Cardamom mountains in south-west Cambodia.

The two new facilities were intended to make sassafras oil from the roots of the extremely rare Mreah Prew Phnom tree for export to neighbouring countries.

Sassafras oil is used to make cosmetics, but it can also be used as a precursor chemical to make methylenedioxymethamphetamine, more commonly known as the recreational drug ecstasy.

FFI was alarmed that the rate of the illegal production of the "ecstasy oil" could have wiped out the Mreah Prew Phnom tree within five years. The trees are felled and the excavated roots mechanically shredded and boiled in a cauldron during a process that takes about 12 hours to produce 30 litres of oil.

Idiotic street value figures aside, a good piece; I wonder how substitutable this precursor (safrole?) is, in terms of organic sources at least. Is this damage a function of prohibition? One is inclined to assume so; at the very least, it makes it impossible to source the compound from sustainable forestry/agriculture.

Deeply screwed up on a shamanic level, too - the mother of those trees must be PISSED...

Posted By Psychotrophic at 2009-02-26 16:35:01 permalink | comments
Tags: mdma ecocrime deforestation
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Molli. : 2009-04-19 14:50:10
Ah yes, prohibition is bliss as well as ignorance. Ignorant people = prohibition....Nice work
Acme_Rocket. : 2009-03-14 19:42:08
All the more reason why we shouldn't layoff process chemists.
shky. : 2009-03-10 02:05:57
Acme_Rocket> Keep it under your hat, but excellent addition to the conversation. There are a number of more sustainable sources of safrole, and there are of course as you mention methods of fabricating the material required without use of plants that aren't being replaced. Additionally, this is definitely a note indicating the need for regulation. Seriously man...how much of the planet do we have to profiteer off before we decide to just deal with drugs rationally, and not as an anticulture defining boojum.
Acme_Rocket. : 2009-02-27 00:04:01
Scratch the last part about the one-step Wittig reaction. Look into Pd catalyzed cross-coupling.
Acme_Rocket. : 2009-02-26 23:12:04
The synthetic challenge of the MDMA molecule is the 1,2 methylenedioxy aryl substituent. The transformation from piperonal to safrole is only one reaction (ex. Wittig, but some more efficient would be required for scale-up). Whether industry isolates that base precursor from natural sources or commodity chemicals, I'm uncertain. The rest of the chemicals required for the transformation are common.
You could make LSD from something as simple as indole, but it would require many steps after that to reach the final structure.
With enough research you could probably design a synthesis of MDMA or LSD using more modern synthetic methods, that could make the recipes in PhiKaL or TiHKaL seem ancient by comparison (although many of the reactions would be unchanged). You could probably even design an enantiopure synthesis with enough time and effort.
siekostoner. : 2009-02-26 20:27:34
i've never heard of any way to make MDMA without using safrole as a precursor...... please correct me if i'm wrong

using safrole as a precursor to MDMA is no different from using lysergic acid (from ergot) to make LSD, which is again, to my knowledge, the only way to do it

Acme_Rocket. : 2009-02-26 20:19:30
Like most chemicals derived from natural products used widely today (ex. Taxol) you need to go completely synthetic to feed the masses. Wanna find out who's making it, look for the person/company buying up 4,5 methylenedioxy benzaldehyde (piperonal). It's only about $25 dollars for 100 grams retail.
Ahhhhhh. : 2009-02-26 19:31:13
Prohibition is bliss. Mantra Mantra Mantra- Chant with me.............. Prohibition is Bliss Prohibition is bliss Prohibition is bliss
Murple. : 2009-02-26 16:54:59
If it were regulated, this wouldn't be an issue. Instead, the farmers make the oil that contains a highly suspected carcinogen with no precautions and don't plant new ones. Why? Time is money and they don't have time to do it unless they're forced to.

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