What is Spheramine(R)?
Browsing the nets today I came across a novel therapy for Parkinson's called Spheramine. Since Parkinson's is a dopamine related disorder I checked it out. Seems they are injecting this stuff directly into the brain, no kidding. But what is it? It is no typical pharm chemical, this is some weird shat:
Spheramine is a novel cell-based therapy with promise for the treatment of moderate to advanced Parkinson's disease (PD). Spheramine consists of human retinal pigment epithelial (hRPE) cells attached to a Microcarrier Support Matrix (MSM) for enhanced hRPE cell survival. These cells are found in the inner layer of the retina and produce levodopa. Spheramine is administered in the brain where the levodopa created by hRPE cells is presumably converted into dopamine, the neurotransmitter that is decreased in PD due to a progressive loss of dopaminergic neurons. Spheramine has been granted Fast Track and Orphan Drug status by the FDA.
Looks like they're investigating it for use in an artificial gland implant. Hmm... Do I smell an Erowid Spheramine Vault in the near future?
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