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Genes outwit doping test

Doping will always be a scandal in pro sports, but what if some mutant athletes could take steroids without it being detected in a urine test? Turns out that for some people this is exactly the case:

The 55 men in a drug doping study in Sweden were normal and healthy. And all agreed, for the sake of science, to be injected with testosterone and then undergo the standard urine test to screen for doping with the hormone.

The results were unambiguous: the test worked for most of the men, showing that they had taken the drug. But 17 of the men tested negative. Their urine seemed fine, with no excess testosterone even though the men clearly had taken the drug.

It was, researchers say, a striking demonstration of a genetic discovery. Those 17 men can build muscles with testosterone, they respond normally to the hormone, but they are missing both copies of a gene used to convert the testosterone into a form that dissolves in urine. The result is that they may be able to take testosterone with impunity.

Doping with impunity? I like the sound of that.

Posted By jamesk at 2008-04-30 11:51:37 permalink | comments
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