Chemists vs. law in quest for legal highs

Mr. Llewellyn, a self-described former crack addict, started out making mephedrone, a stimulant also known as Meow Meow that was already popular with the European clubbing set. Once governments began banning it earlier this year, Mr. Llewellyn and a chemistry-savvy partner started selling something they dubbed Nopaine -- a stimulant they concocted by tweaking the molecular structure of the attention-deficit drug Ritalin.

Nopaine "is every bit as good as cocaine," says Mr. Llewellyn, who has lived in Antwerp on and off since the late 1980s. "You can freebase it. You can snort it like crack." Still, he emphasized, "Everything we sell is legal. I don't want to go to jail for 14 years."

Mr. Llewellyn is part of a wave of laboratory-adept European entrepreneurs who see gold in the gray zone between legal and illegal drugs. They pose a stiff challenge for European law-enforcement, which is struggling to keep up with all the new concoctions. Last year, 24 new "psychoactive substances" were identified in Europe, almost double the number reported in 2008, according to the Lisbon-based European Monitoring Centre for Drugs and Drug Addiction, or EMCDDA.

The problem is also touching U.S. shores. A new synthetic drug similar to marijuana is increasingly popular, for instance. Some states have started banning it. But many of the other substances and stimulants vexing Europe are less of an issue in the U.S., according to a spokeswoman for the Drug Enforcement Administration.

[Thanks Sam Hell!]