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Synthetic marijuana's effect on brain

K2 is a combination of plant materials and two synthetic cannabinoids, according to Jeremiah Morris, a forensic scientist for the Johnson County Criminalistics Laboratory in Mission, Kan. The laboratory ran an analysis on K2 in October 2009 after noticing an increase in use in Johnson County.

"They found K2 to contain lab-produced drugs that act on the same part of the brain as marijuana," Morris said.

But the compounds in K2 are three to five times more potent than THC found in marijuana. Morris compared the effects of K2's compounds to a lock-and-key mechanism in which the lock is a receptor site of the brain and the key is the drug's compounds. The "keys" in K2 compounds are keys that fit the brain's "lock" better than those in marijuana.

[Thanks Thomas!]

Posted By jamesk at 2010-02-18 11:41:17 permalink | comments
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Micah. : 2011-03-30 07:39:36
Hmmm. They don't care about the American public in the least. They started banning K2 and other incense products long before they actually started research on any possible side effects they may have. Please don't be fooled into thinking they care about our well-being. If that were so, they would just tear down the corrupt FDA and take out Big Pharma as they are the biggest toxin pushers! Provided there are age restrictions, if someone wants some k2 herb, who are you to tell them that they can't have it? If someone wants to, they will buy k2 smoke whether it's legal or not as that is what happens with anything else that is unjustly and ridiculously prohibited. K2 incense will be no different. Plus, the formulas are constantly changing. [link] offers several products that are legal all over the world.
baboocla jamica . : 2011-03-14 07:01:36
i thinks we should legliase it becouse it is good for the people becouse it relifes painand stress related problmes.
long live rastafreian people "peace out"
Lana. : 2010-09-14 08:12:34
I wish people would be more careful. My friends were telling me about some sort of blueberry K2 incense and I googled it and found out it is counterfeit. Apparently there are only a few authentic blends so the list of fakes is scary long and they don't quite know what is in those, [link] It's worth checking out if you buy this or know someone who does. Stay safe.....
Aubree. : 2010-07-14 12:54:07
The scary thing though is a lot of people aren't even getting real k2 incense. This website has a longggg list of known counterfeit k2... [link]
strangetou. : 2010-02-19 20:55:34
Just tried k-2 blonde...I like it...the problem is gonna come with the government trying to regulate it. The country is already in trouble.. might as well ease the economy and everyones pockets by legalizing weed.. otherwise if this k-2 isnt illegal...alot of people will be smoking it and the ASIANS>>>make all the money off of us...
avicenna : 2010-02-18 21:55:02
Many office, school and hotel locks have a "master" key that will unlock any of them as well as one door only keys that open only one. Some cars come with a regular key that works everywhere and a valet key that will operate the ignition and doors but won't open the trunk.

Have you ever had a copy of a key made and the copy is a little finicky or bent or nicked a key, so that you have to jiggle it around a bit to get it to work? That seems a lot like what's going on with receptors.

If you want to point out the limits of the analogy, I'd go more for something about the electrical-magnetic properties mattering for receptor binding but not for locks and keys.

Even so, that doesn't mean the analogy is bad. As George Box said: All models are wrong, but some are useful. I think that synthetic cannabinoids are a good example of how the lock and key model can be useful.

Stashinsbrot. : 2010-02-18 13:25:20
Lock and key analogy = bad likening.

How many locks take different kinds of keys?

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